生命科学研究2013,Vol.17Issue(3):278-282,5.
DNA甲基化与多发性骨髓瘤
DNA Methylation and Mutiple Myeloma
摘要
Abstract
DNA methylation is one of the most widely studied epigenetic events in tumor research.DNA methylation usually occurs at CpG island.DNA methylation is mediated by DNA methyhransfeases (DNMTs).DNA methylation plays an important role in the development and progression of lots of cancers.A great number of studies had indicated a strong correlation between the multiple myeloma (MM) and methylation.Further studies on the MM associated methylation may provide new sights into MM pathogenesis and its diagnosis and treatment.关键词
甲基化/基因/多发性骨髓瘤(MM)Key words
methylation/gene/multiple myeloma (MM)分类
医药卫生引用本文复制引用
张家铭,胡维新..DNA甲基化与多发性骨髓瘤[J].生命科学研究,2013,17(3):278-282,5.基金项目
国家自然科学基金资助项目(81071947) (81071947)
中南大学研究生自主探索创新基金资助项目(2012zzts131) (2012zzts131)