现代检验医学杂志2013,Vol.28Issue(3):10-12,3.DOI:10.3969/j.issn.1671-7414.2013.03.003
器官移植领域的生物标志物:IMPDH
Biomarker in the Field of Organ Transplantation:IMPDH
摘要
Abstract
Inosine 5'-monophosphate dehydrogenase(IMPDH) is the rate limiting enzyme in the de novo synthesis of guanine nucieotides. The direct determination of target enzyme activity as a biomarker of mycophenolic acid (MPA) may help to estimate better the individual response to the immuno suppressant. The purpose of this review is to provide an overview of the recent literature on the methodology and the use of IMPDH monitoring in the field of organ transplantation.关键词
生物标志物/次黄嘌呤核苷5'-一磷酸脱氢酶/器官移植Key words
biomarker/ ionosine 5'-monophosphate dehydrogenase/organ transplantation分类
医药卫生引用本文复制引用
王继贵..器官移植领域的生物标志物:IMPDH[J].现代检验医学杂志,2013,28(3):10-12,3.