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器官移植领域的生物标志物:IMPDH

王继贵

现代检验医学杂志2013,Vol.28Issue(3):10-12,3.
现代检验医学杂志2013,Vol.28Issue(3):10-12,3.DOI:10.3969/j.issn.1671-7414.2013.03.003

器官移植领域的生物标志物:IMPDH

Biomarker in the Field of Organ Transplantation:IMPDH

王继贵1

作者信息

  • 1. 中南大学湘雅二医院,长沙,410011
  • 折叠

摘要

Abstract

Inosine 5'-monophosphate dehydrogenase(IMPDH) is the rate limiting enzyme in the de novo synthesis of guanine nucieotides. The direct determination of target enzyme activity as a biomarker of mycophenolic acid (MPA) may help to estimate better the individual response to the immuno suppressant. The purpose of this review is to provide an overview of the recent literature on the methodology and the use of IMPDH monitoring in the field of organ transplantation.

关键词

生物标志物/次黄嘌呤核苷5'-一磷酸脱氢酶/器官移植

Key words

biomarker/ ionosine 5'-monophosphate dehydrogenase/organ transplantation

分类

医药卫生

引用本文复制引用

王继贵..器官移植领域的生物标志物:IMPDH[J].现代检验医学杂志,2013,28(3):10-12,3.

现代检验医学杂志

OACSTPCD

1671-7414

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