现代检验医学杂志2013，Vol.28Issue(3)：92-94,3.DOI:10.3969/j.issn.1671-7414.2013.03.029
神经元特异性烯醇化酶(NSE)在早期脑挫裂伤诊断中的意义
Diagnostic Value of NSE(Nuron Specific Enolase)in the Patients of Early Brain Contusion and Laceration
王欣 1谢国强 2任超杰 1罗婷3
作者信息
- 1. 陕西省核工业咸阳215医院检验科,陕西咸阳,712000
- 2. 陕西省核工业咸阳215医院神经外科,陕西咸阳,712000
- 3. 陕西武警总队机关门诊部,西安,710054
- 折叠
摘要
Abstract
Objective To investigete the diagnostic value of NSE(nuron specific enolase) to the patients with early brain contusion and laceration. Methods Studying the investigation by contrasting different medical case of illness, 90 specimen (56 male,34 female)were from healthy people who were not puzzled by lung disease and nervous system diseases,and the average age of them was 36 yearsold. In contrast, 121 specimen (70 male, 51 female) with early brain contusion and laceration were from the 215 hospital patients who were diagnosed by CT or MRI,the average age of which was 38. 7 years old,the case includes mild head injury 73 patients,and 48 patients of severe traumatic brain injury. Using ECLIA to detect the NSE concentration of the serum,and Student t test was used for statistical analysis of serum NSE level differences in traumatic brain injury patients and healthy population. Results The NSE level of severe traumatic brain injury was 26. 5 ± 12. 3 ng/L, and the NSE level of mild traumatic brain injury was 18. 7 ± 9. 1 ng/L. In contrast,the NSE level of healthy population was 10. 3 ± 3. 2 ng/L. The contrast value of t-test with the first case and the second case were 2. 986 and 3. 152 respectively,then P<0. 01. The value of t-test with the mild injury and the severe injury was 2. 076 (P<0. 05). Could conclude that the NSE level of 121 cases with early brain contusion and laceration was higher than the control group significantly. Conclusion NSE test can be regarded as an valuable quota in the diagnosis of brain contusion and laceration or estimate the degree of injury.关键词
神经元特异性烯醇化酶(NSE)/脑挫裂伤/诊断Key words
Neuron-specific enolase/ brain contusion and laceration/ diagnosis分类
医药卫生引用本文复制引用
王欣,谢国强,任超杰,罗婷..神经元特异性烯醇化酶(NSE)在早期脑挫裂伤诊断中的意义[J].现代检验医学杂志,2013,28(3):92-94,3.
