现代检验医学杂志2013，Vol.28Issue(3)：103-105,109,4.DOI:10.3969/j.issn.1671-7414.2013.03.032
sCD36预测2型糖尿病发生血管病变的实验研究
Experimental Study for sCD36 in Predicting Complications of Vascular Disease in Type 2 Diabetic Patients
鲁礴 1吕玉梅 1杨玉梅 1曾君才 1范金涛 1张欣1
作者信息
- 1. 襄阳市东风人民医院,湖北襄阳,441004
- 折叠
摘要
Abstract
Objective To investigate the level and the clinical significance of plasma soluble CD 36(sCD36) in predicting complications of vascular disease in type 2 diabetic patients. Methods To test the serum level of sCD36,insulin resistance index (IR) ,triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in 45 type 2 diabetic patients with vascular disease (group A) ,47 type 2 diabetic patients with non-vascular disease (group B) and 45 normal controls (group C) from August, 2008 to May, 2012. Satistical analysis was used to reveal the clinical relationship among vascular disease in type 2 diabetic group,non-vascular disease in type 2 diabetic group and the healthy control group. Results sCD36 levels was significantly higher in type 2 diabetic patients (3. 25 ± 0. 3 ,1. 55 ±0. 31, t= 11. 23, P<0. 05). Compared with the healthy control group (3. 25 ± 0. 3,1. 55 ± 0. 31,t=3. 44,P<0. 05) ,the difference was significant (P<0. 05). In patients with type 2 diabetes,the levels of sCD36 in group with vascular disease complication were significantly higher in the group with non-vascular disease complication (P<0. 05). Correlation analysis showed that sCD36 was positively associated with IR,TG and LDL-C ( r= 0. 447,0. 442,0. 332,P<0. 05). Conclusion sCD36 was useful for monitoring complications of vascular disease in type 2 diabetic patients.关键词
2型糖尿病/胰岛素抵抗/可溶性CD36/三酰甘油/低密度脂蛋白胆固醇Key words
type 2 diabetes mellitus/ soluble CD 36/ insulin resistance index (IR)/ triglyceride (TG)/ low density lipoprotein cholesterol (LDL-C)分类
医药卫生引用本文复制引用
鲁礴,吕玉梅,杨玉梅,曾君才,范金涛,张欣..sCD36预测2型糖尿病发生血管病变的实验研究[J].现代检验医学杂志,2013,28(3):103-105,109,4.
