应用化学2013，Vol.30Issue(7)：740-744,5.DOI:10.3724/SP.J.1095.2013.20390
含L-氨基酸基团的手性单体及与N-异丙基丙烯酰胺共聚物的合成
Synthesis of Chiral Functional Monomers Containing L-Amino Acid Groups and Their Copolymers with N-Isopropylacrylamide
摘要
Abstract
Three chiral functional monomers containing L-phenylalanine(L-Phe),L-tryptophane(L-Trp) and L-leucine(L-Leu) were designed and synthesized and used as precursors for preparing of chiral polymers.After esterification and condensations,AAc-L-Phe (AAc:acrylic acid),AAc-L-Trp and AAc-L-Leu were obtained and characterized by IR and 1 H NMR.Then the subsequent copolymerization between AAc-L-Phe and N-isopropylacrylamide (NIPAam) was carried out in different mass ratio.The resulted polymers were identified by IR and differential scanning calorimetry (DSC) and proved that all of them are optical active and thermo-sensitive materials.The successful synthesis of chiral polymers suggested that these chiral monomers can be applied to the preparation of chiral polymers.关键词
手性/L-氨基酸/合成/手性单体/共聚物Key words
chirality/ L-amino acids/ synthesis/ functional monomers/ copolymer分类
化学化工引用本文复制引用
时东新,陈娇娇,杜显丽,王乐乐,蒋奕,任绒绒..含L-氨基酸基团的手性单体及与N-异丙基丙烯酰胺共聚物的合成[J].应用化学,2013,30(7):740-744,5.基金项目
国家自然科学基金(20904039)、天津市应用基础及前沿技术研究计划(10JCYBJC02900)资助项目 （20904039）
