中国感染控制杂志2013，Vol.12Issue(3)：202-204,207,4.DOI:10.3969/j.issn.1671-9638.2013.03.012
糖尿病与非糖尿病患者社区获得性肺炎临床特点与病原学
Clinical characteristics and etiology of community-acquired pneumonia in diabetic and non-diabetic patients
方琦 1方铭喜 1姚蔚 1盛飞英 1陈敏1
作者信息
- 1. 上海市浦东新区周浦医院,上海,201318
- 折叠
摘要
Abstract
Objective To analyze clinical characteristics of community-acquired pneumonia (CAP)in diabetic and non-diabetic patients. Methods From January 2008 to May 2011 ,100 CAP patients in a hospital were selected, 50 of whom had diabetes (group A) and 50 without diabetes (group B), their clinical data were analyzed. Results The average length of hospital stay in group A was significantly longer than that of group B ([18. 52 ± 4. 32] d vs [12. 64 ±4. 18] d, x2 = 6. 92,P＜0. 01); serum alanine aminotransferase (ALT) and aspartate transaminase (AST) in group A were significantly higher than group B ([52. 26 ± 15. 18] U/L vs [40. 39 ± 15. 42] U/L; [48. 44 ± 10. 25] U/L vs [35. 70 ± 9. 98] U/L, P＜0. 05, respectively); blood urea nitrogen (BUN) and serum creatinine (SCr) in group A were significantly higher than group B ([8. 02 ± 2. 12] mmol/L vs [5. 35 ± 1. 99] mmol/L; [128. 05 ± 21. 25] μmol/L vs [98. 20 ± 20. 93) μmol/L, P ＜0. 05, respectively). Mixed infection rate in group A was significantly higher than group B (26. 00% vs 10. 00%); metabolic syndrome and incidence of macrovascular complications were significantly higher than group B (28. 00% vs 12. 00%; 36. 00% vs 10. 00%, P＜0. 05, respectively). Rate of severe pneumonia and mortality in group A was 12. 00% (6 cases) and 6. 00% (3 cases) respectively,and group B was 4. 00% (2 cases) and 2. 00% (1 case) respectively, sputum culture positive rate in group A and B was 82. 00% (41/50) and 88. 00% (44/50) respectively, Streptococcus pneumoniae (16 isolates in group A and 17 in group B) and Klebsiella pneumoniae (4 isolates in group A and 5 in group B)were common in both groups. Conclusion Diabetic patients with CAP have long disease course, with severe illness and multiple complications, controlling blood glucose is the basis of treatment, anti-infection is the key, and improving nutritional state and organ function is important aspect.关键词
糖尿病/肺炎/社区获得性肺炎/病原学/感染Key words
diabetes/ pneumonia/ community-acquired pneumonia/ etiology/ infection分类
医药卫生引用本文复制引用
方琦,方铭喜,姚蔚,盛飞英,陈敏..糖尿病与非糖尿病患者社区获得性肺炎临床特点与病原学[J].中国感染控制杂志,2013,12(3):202-204,207,4.
