摘要
Abstract
Objective To compare the efficacy and safety of intravenous iron sucrose and oral iron therapy for pregnancy with anemia,the new method was explored.Methods All of 40 patients with cervical cancer were randomly divided into experiment group (20 cases) and the control group (20 cases).The experiment group is received 200 mg intravenous iron sucrose plus 100 mL 0.9％ sodium chloride injection,while the control group is provided with compound ferrous sulfate and folic acid tablets,with 4 pills one time and 3 times a day for 4 weeks.The level of hemoglobin (Hb),hematokrit (Hct),serum ferritin (SF) and transferrin saturation (TSAT) of two groups were compared before and after therapy.Results The levels of Hb,Hct,SF and TSAT of patients significantly increased at 4 weeks after drug therapy (P ＜ 0.05),the levels of Hb,Hct,SF and TSAT of experiment group were significantly higher than those of control group (P ＜ 0.05).No adverse event was found in experiment group,while there were 3 cases with adverse gastrointestinal effects in control group.Conclusion Intravenous iron sucrose is effective and safe in improving iron deficiency anemia in pregnancy.关键词
蔗糖铁注射液/口服铁剂/产科贫血/血红蛋白/血清铁蛋白Key words
iron sucrose injection / oral iron / anemia in pregnancy / hemoglobin/ serum ferritin分类
医药卫生
