中国农业科学2013,Vol.46Issue(4):819-829,11.DOI:10.3864/j.issn.0578-1752.2013.04.016
全基因组关联分析在畜禽中的研究进展
Progresses in Research of Genome-Wide Association Studies in Livestock and Poultry
摘要
Abstract
Genome-wide association study (GWAS) is a new research method for complex traits developed in recent years.In the last several years,many GWAS were performed focusing on economically important traits,genetic defect diseases,resistant or susceptible ability to complex diseases,breed characteristics of the main livestock and poultries.These studies not only enlarged molecular markers used in the marker-assisted selection,but provided important information for elaborate the genetic mechanism of these traits.In this study,the populations,main statistical methods and results of the GWAS in main livestock and poultry were reviewed.Furthermore,some prospect of GWAS in the future was made.This review will provide reference for further research on genetic background of the important traits of livestock and poultry by GWAS.关键词
全基因组关联分析(GWAS)/畜禽/遗传变异/单核苷酸多态性(SNP)Key words
genome-wide association studies (GWAS)/ livestock and poultry/ genetic variation/ single nucleotide polymorphism (SNP)引用本文复制引用
王继英,王海霞,迟瑞宾,郭建凤,武英..全基因组关联分析在畜禽中的研究进展[J].中国农业科学,2013,46(4):819-829,11.基金项目
优质肉猪新品种(配套系)选育研究(2010LZ013-01)、转基因生物新品种培育重大专项(2011ZX08006-005)、国家生猪产业技术体系(CARS-36)、山东省农业产业技术体系生猪创新团队建设项目 (配套系)