中国全科医学2013，Vol.16Issue(12)：1324-1326,3.DOI:10.3969/j.issn.1007-9572.2013.04.077
半合成四环素类抗生素在多发性硬化中的应用研究进展
The Applications of Semi-synthetic Tetracycline Antibiotic in the Treatment of Multiple Sclerosis
肖凤娟 1李作孝1
作者信息
- 1. 646000,四川省泸州市,泸州医学院附属医院神经内科
- 折叠
摘要
Abstract
The semi - synthetic tetracycline antibiotic is a tetracycline derivative. The present study has shown that a-side from its antibiotic activities ( bacteriostatic and anti - inflammatory effect), it also has non - antibiotic activities, including anti - oxidation and anti - apoptosis properties. In clinical it has been served as a neuroprotective agent for the treatment of stroke, multiple sclerosis and other acute and chronic neurological diseases. In this paper, the mechanism of semi - synthetic tetracycline antibiotics ( minocycline and doxycycline ) treating multiple sclerosis will be mainly reviewed.关键词
四环素类/米诺环素/多西环素/多发性硬化Key words
Tetracyclines/ Minocycline/ Doxycycline/ Multiple sclerosis分类
医药卫生引用本文复制引用
肖凤娟,李作孝..半合成四环素类抗生素在多发性硬化中的应用研究进展[J].中国全科医学,2013,16(12):1324-1326,3.
