摘要
Abstract
Objective To analyze the relationship between red blood cell distribution width ( RDW ) and coronary artery disease ( CAD ). Methods RDW, hemoglobin ( HGb ), red blood cell count ( RBC ), white blood cell count ( WBC ), mean corpuscular volume ( MCV ), hematocrit ( Hct), platelet count ( PLT ), mean platelet volume ( MPV ), blood urea nitrogen ( BUN ), serum creatinine ( Cr ), blood uric acid ( UA ), alanine aminotransferase enzyme ( ALT ), aspartate amin-otransferase ( AST), albumin, blood lipids were determined in 81 healthy subjects ( control group ) and 224 CAD patients ( CAD group ) including 110 patients with angina pectoris and 114 with acute myocardial infarction. The results were analyzed comparatively; Gensini score performed in CAD group based on coronary angiography; the correlation of Gensini score with RDW analyzed. Multivariate logistic regression analysis was used to evaluate the independent risk factors of CAD. Results As compared with control group, RDW increased in CAD group, the difference was significant [ ( 12.38 ?.64 )% vs. ( 12. 17 ?.45 )% , P <0. 01 ]. By pearson correlation analysis, RDW was positively correlated with age, BUN, Cr, Gensini score ( r- 0.233, 0.222, 0. 120, 0. 199; P all < 0.01 ). Multiple linear regression analysis showed that age, Gensini score were independent influencing factors of RDW. Multivariate logistic regression analysis showed that the independent risk factors predicting CAD included smoking, diabetes, RDW and TG. Conclusion RDW, associated with the severity of coronary artery stenosis, is an independent influencing factor for CAD.关键词
红细胞体积分布宽度/冠心病/冠状血管造影术/Gensini积分Key words
Red blood cell distribution width/ Coronary disease/ Coronary angiography/ Gensini score分类
医药卫生
