中国全科医学2013,Vol.16Issue(16):1856-1858,3.DOI:10.3969/j.issn.1007-9572.2013.06.012
H型高血压与急性脑梗死患者预后的关系研究
The Correlation of H Type Hypertension and Prognosis of Patients with Acute Cerebral Infarction
摘要
Abstract
Objective To investigate the correlation of H type hypertension with prognosis of patients with acute cerebral infarction ( ACI ) . Methods A total of 324 ACI patients with hypertension admitted in our hospital between January 2010 and January 2012 were enrolled in this study. The patients were divided into the H type hypertension group ( Hcy≥10 μmol/L; n = 241 ) and the control group ( Hcy < 10 μmol/L; n = 83 ) according to the level of homocysteine ( Hcy ) measured upon admission. The clinical characteristics of the patients were compared between the two groups. National institute of health stroke scale ( NIHSS ), Barthel index ( BI ), and modified Rankin scale ( mRS ) were used to evaluate the functional disability and prognosis of patients upon admission and at 90 days after discharge. Results No significance was found between the two groups in age, sex, systolic blood pressure, history of diabetes, smoking, and hyperlipemia, as well as the level of blood fat, blood glucose, D -Dimer, and hs - CRP upon admission and mortality at 90 days ( P >0. 05 ) . H type hypertension group had higher NIHSS score , lower BI score, and lower proportion of 0 - 2 scoring in mRS than the control group both on admission and at 90 days ( P <0.05). Logistic analysis results showed that H type hypertension [ OR = 2. 447 , 95% CI( 1.878, 5.248), P= 0.027] was an independent risk factor for poor prognosis of ACI. Conclusion ACI patients with H type hypertension have serious neurological dysfunction and poor diagnosis.关键词
高血压/高同型半胱氨酸血症/脑梗死/预后/关系Key words
Hypertension/ Hyperhomocysteinemia/ Brain infarction/ Prognosis/ Relationship分类
医药卫生引用本文复制引用
王晶,刘晶晶,吴杨,刘家丰,于洋..H型高血压与急性脑梗死患者预后的关系研究[J].中国全科医学,2013,16(16):1856-1858,3.基金项目
黑龙江省卫生厅科研项目(2010-308) (2010-308)
哈尔滨市科技创新人才基金(RC2011QN003027) (RC2011QN003027)