中国实用儿科杂志2013，Vol.28Issue(7)：512-515,4.
儿童紫癜性肾炎足突融合与肾脏病理分级相关性研究
Discussion of relationship between renal pathology and glomerular podocyte injury in childhood Henoch-Sch(o)nlein purpura nephritis.
摘要
Abstract
Objective To analyze relationship between renal pathology and glomerular podocyte food processes fused in childhood Henoch-Sch(o)nlein purpura nephritis.Methods Renal pathological types of 72 children suffering from HSPN were reviewed during the period from January 1st 2008 to January 1st 2011 from Nanjing Command of Jingling Hospital.Pathological grading and immunofluorescence typing were analyzed.The information of podocyte food processes fused was showed by electron microscopy.Results Pathological findings were classified as ISKDC (the International Society of Kidney Disease in Children) grade Ⅱ in 34 (47.2％) and grade Ⅲ in 38 (52.8％).Glomerular podocyte injury was classified by electron microscope as food processes of podocyte fused extensively in 21 cases,food processes of podocyte fused segmentally in 35 cases,food processes of podocyte without fusion in 1 lcases.There was no renal glamorous in nephridial tissue by electron microscope in five cases.Conclusion The childhood HSPN is expressed with foot process of podocytes fused more extensively on electron microscope besides glomerular pathologic change.The more serious the degree of podocyte injury is,the more obvious the pathologic changeis.关键词
紫癜性肾炎/病理分级/足细胞损伤/儿童Key words
Henoch-Sch(o)nlein purpura nephritis/ renal pathology/ glomerular podocyte injury/ children分类
医药卫生引用本文复制引用
任献国,张沛,杜丽芳,高远赋,樊忠民,高春林,茅松,何旭,夏正坤..儿童紫癜性肾炎足突融合与肾脏病理分级相关性研究[J].中国实用儿科杂志,2013,28(7):512-515,4.基金项目
"十一五"国家科技支撑计划(2006BAI04A16) （2006BAI04A16）
