中国药房2013，Vol.24Issue(23)：2161-2163,3.DOI:10.6039/j.issn.1001-0408.2013.23.17
黄芩素滴丸的质量标准研究
Study on Quality Standards of Baicalein Dropping Pills
摘要
Abstract
OBJECTIVE:To establish the quality standards of Baicalein dropping pills.METHODS:Baicalin of Baicalein dropping pills was identified qualitatively by TLC;the content of baicalin was determined by HPLC.At the same time,the preparation was detected according to the general requirements of dropping pills in 2010 edition Chinese Pharmacopoeia.RESULTS:The chromatographic spots of samples showed the same colors in the same position with control agents by TLC,without interference from negative control agents.The linear range of baicalein were 0.519 75-1.559 25 μg; RSDs of precision,repeatability and stability were less than 2％ ; average recovery was 97.61％ (RSD=1.10％,n=6) ; the weight variation,microbial limit tests and disintegration time were all fitted with the requirements of 2010 edition Chinese Pharmacopoeia.CONCLUSIONS:The standard can be used for quality control of Baicalein dropping pills.关键词
黄芩素滴丸/质量标准/薄层色谱法/高效液相色谱法/黄芩苷Key words
Baicalein dropping pills/ Quality standards/ TLC/ HPLC/ Baicalin分类
医药卫生引用本文复制引用
杨新建,王雷,梁颖..黄芩素滴丸的质量标准研究[J].中国药房,2013,24(23):2161-2163,3.基金项目
天津市科技发展计划资助项目(No.033180311) （No.033180311）
