摘要
Abstract
OBJECTIVE:To observe the clinical efficacy of Qirong runchang oral liquid combined with lactulose in the treatment of senile functional constipation.METHODS:120 elderly patients with functional constipation were randomly divided into group A,B,C with 40 cases in each group.The patients in group A received Qirong runchang oral liquid combined with lactulose (oral,Qirong runchang oral liquid 20 ml each time,3 times a day; lactulose 30 ml,at breakfast,amount added to 60 ml because there was no significant effect 2 days later) ; patients in group B received Qirong runchang oral liquid (oral,20 ml each time,3times a day) ; patients in group C received lactulose (oral,30 ml,at breakfast,amount added to 60 ml because there was no significant effect 2 days later).Treatment course lasted for 4 weeks.The total clinical effective rate,recurrence rate and adverse drug reactions were calculated before and after treatment with defecation interval,phenotypic changes,difficult defecation degree,vitals and assistant examination as index.RESULTS:The total effective rates of group A,B,C were 97.5％,82.5％ and 80％ after 4 weeks treatment,and the recurrence rate were 7.5％,17.5％ and 20.0％,and the incidence of adverse reaction were 5％,7.5％and 7.5％,respectively.CONCLUSIONS:The effect of Qirong runchang oral liquid combined with lactulose is better than them alone in the treatment of senile functional constipation with less adverse drug reaction,which can provide reference for clinical use of drugs.关键词
芪蓉润肠口服液/乳果糖/功能性便秘/高龄/老年人/疗效Key words
Qirong runchang oral liquid/ Lactulose/ Functional constipation/ Advanced age/ Elderly people/ Therapeutic efficacy分类
医药卫生
