中国中西医结合影像学杂志2013，Vol.11Issue(3)：250-252,255,4.DOI:10.3969/j.issn.1672-0512.2013.03.007
不同b值下的ADC值对肺部病变诊断的价值
Different b value on ADC in diagnosis of lung cancer
摘要
Abstract
Objective:To evaluate the application of ADC value using different b value in the diagnosis of pulmonary benign and malignant mass.Methods:70 patients with chest MRI DWI scan using different b value (0,500,700,900 s/mm2).70 lesions were analyzed based on the postoperative pathological or puncture biopsy of all lesions as standard,and two independent samples t test was used for statistical analysis of the information obtained.Results:The ADC value differences were statistically significant between benign group and malignant group with the b value of 500 s/mm2,700 s/mm2,900 s/mm2 (P ＜0.01).Taking upper limit of 95 ％ confidence interval of ADC value in the malignant group as a diagnostic threshold,the diagnostic threshold was 1.687 × 10-3 mm2/s,1.465 × 10-3 mm2/s,1.543 × 10-3 mm2/s with b value of 500 s/mm2,700 s/mm2,900 s/mm2,respectively.Using ROC curve to analyze ADC threshold role in the diagnosis of malignant lesions in different b value,b value of 700 s/mm2 had maximum value when the diagnostic sensitivity,specificity,coincidence rate,positive and negative predictive values were 92.86％,76.92％,82.50％,93.57％ and 66.67％,respectively.Conclusion:The optimal b value is 700 s/mm2.关键词
肺疾病/磁共振成像,弥散Key words
Lung diseases/ Diffusion magnetic resonance imaging分类
医药卫生引用本文复制引用
于伟伟,张成琪,李嵩,王广丽..不同b值下的ADC值对肺部病变诊断的价值[J].中国中西医结合影像学杂志,2013,11(3):250-252,255,4.基金项目
山东省科技计划发展项目(2009GG10002040). （2009GG10002040）
