中华临床免疫和变态反应杂志2013，Vol.7Issue(2)：151-153,3.
利妥昔单抗治疗系统性红斑狼疮出现血栓栓塞并文献复习
Thrombosis Associated with Rituximab Therapy in Lupus Patients: A Rare Adverse Effect
摘要
Abstract
Objective Thrombosis associated with rituximab is rare. We study the clinic manifestation of the patient who developed severe thrombosis after treated with rituximab in order to learn more about side-effects of rituximab. Methods A patient with systemic lupus erythematosus ( SLE) complicated with anti phospholipid syndrome ( APS) , who was developed severe thrombosis after treated with rituximab, is described in detail. Results A patient was improved after rituximab treatment. But the patient developed deep vein thrombosis and pulmonary embolism three months after rituximab therapy. Conclution Rituximab is effective in SLE, but it has also been associated with some potentially severe adverse effects such as thrombosis.关键词
利妥昔单抗/血栓/狼疮Key words
rituximab/ thrombosis/ lupus分类
医药卫生引用本文复制引用
苏金梅,陈华,徐东,周炜洵,张烜,张奉春..利妥昔单抗治疗系统性红斑狼疮出现血栓栓塞并文献复习[J].中华临床免疫和变态反应杂志,2013,7(2):151-153,3.基金项目
国家自然科学基金(30901342) （30901342）
