中山大学学报（医学科学版）2013，Vol.34Issue(3)：461-465,5.
妊娠期糖尿病患者血清同型半胱氨酸检测及临床意义
Determination of Plasma Homocysteine in Gestational Diabetes Mellitus and Its Clinical Significance
李茂宇 1贺晶2
作者信息
- 1. 浙江大学医学院附属妇产科医院产科,浙江杭州310006
- 2. 浙江省湖州市妇幼保健院产科,浙江湖州313000
- 折叠
摘要
Abstract
[Objective] To investigate clinical significance of gestational diabetes mellitus (GDM) by detecting the level of homocysteine.[Methods] A total of 153 cases of GDM gravida were selected as observation group in Huzhou Women's and Children's Hospital from May 2012 to August 2012,and they were divided into group A1 and A2 according to the blood glucose level.90 cases healthy pregnant women were selected as control group during the same period.Serum homocystein concentration was studied of all the cases,and the correlation between homocysteine and pregnancy outcomes was analyzed.[Results] The serum HCY level in group A2 (11.98 ± 4.05) was significantly higher than that in group A1(8.88 ± 2.63) and control group (8.86 ± 2.48) (P＜ 0.01).Univariate analysis showed that age,weight,parity,gestational age,HCY,fasting blood glucose affect the incidence of maternal and infant adverse outcomes of pregnancy.Logistic regression analysis revealed that the gestational age and HCY are independent factors influence the outcome of pregnancy.[Conclusion] Serum homocysteine level is closely related to the development of gestational diabetes and pregnancy outcome.Monitoring blood HCY may be more help to determine the risk of the occurrence of adverse outcomes of gestational diabetes mellitus than monitoring single blood glucose.关键词
同型半胱氨酸/妊娠期糖尿病/血糖Key words
homocysteine/ gestational diabetes mellitus/ blood glucose分类
医药卫生引用本文复制引用
李茂宇,贺晶..妊娠期糖尿病患者血清同型半胱氨酸检测及临床意义[J].中山大学学报（医学科学版）,2013,34(3):461-465,5.
