同济大学学报（医学版）2013，Vol.34Issue(3)：40-43,48,5.DOI:10.3969/j.issn1008-0392.2013.03.010
24 h食管pH-阻抗联合监测诊断胃食管反流病的价值评估
The value of 24 h ambulatory impedance-pH in diagnosis of gastroesophageal reflux disease
摘要
Abstract
Objective To investigate the value of 24 h ambulatory impedance-pH in diagnosis of gastroesophageal reflux disease (GERD).Methods One hundred and forty two patients with typical reflux symptoms or suggestive of gastroesophageal reflux were included.All patients underwent endoscopy and 24 h ambulatory impedance-pH monitoring.Among them,those with reflux esophagitis or DeMeester score ≥14.72 and SI ≥50％ were defined as GERD + group; others were defined as GERD-group.The parameters of 24 h ambulatory impedance-pH were compared between two groups.Results Among all parameters of 24 h esophageal pH monitoring,DeMeester score,the total time of pH ＜ 4 and time of reflux with pH ＜ 4 for ＞ 5 min had better sensitivity and specificity for diagnosis of GERD.The single parameter of multichannel intraluminal impedance had a low sensitivity (＜ 45％) in diagnosis of GERD.Compared to 24 h esophageal pH monitoring,24 h ambulatory impedance-pH detected more abnormal reflux episodes (x2 =14.65,P ＜ 0.000).Conclusion The results suggest that endoscopy combined with 24 h ambulatory impedance-pH may be a better choice for diagnosis of gastroesophageal reflux disease.关键词
胃食管反流病/多通道阻抗监测/24 h pH监测/Demeester评分Key words
gastroesophageal reflux disease/ multichannel intraluminal impedance/ 24 h esophageal pH monitoring/ Demeester scores分类
医药卫生引用本文复制引用
易丽莎,陈莹,孙会会,姜元喜,许树长..24 h食管pH-阻抗联合监测诊断胃食管反流病的价值评估[J].同济大学学报（医学版）,2013,34(3):40-43,48,5.基金项目
上海市科委临床引导类项目(10411968100) （10411968100）
