现代科学仪器Issue(3):7-13,7.
三重四极杆串联质谱仪碰撞池的研究现状与进展
Introduction to Collision Cell of Triple Quadrupole Mass Spectrometer
摘要
Abstract
Triple quadrupole mass spectrometer is widely employed in the field of environment,food safety and pharma for its excellent quantitation.The parent ions were selected by the first quadrupole (Q1) mass filter before entering the collision cell where they undergo collision induced dissociation to generate product ions,then the daughter ions were mass analyzed by the second quadrupole (Q3) mass filter.The performance of collision cell is quite important for the instrument,most of collision cell has multipoles which are applied with RF and DC to transfer the product ions.Reducing the residence time of product ions in the collision cell can minimize the effect of cross talk in MRM analysis which is one of the most important performance specifications of the triple quadrupole mass spectrometer.Each company has its own patent of collision cell to achieve minimum MRM cross-talk which is used to evaluate the performance of collision cell.To review the development of collision cell in the past few years,the latest designs of collision cells in the triple quadrupole mass spectrometer were presented in this literature.关键词
三重四级杆/串联质谱/碰撞池Key words
Triple Quadrupole/Tandem Mass Spectrometer/Collision Cell分类
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邓丰涛,李纲,刘立鹏,韩双来,王健..三重四极杆串联质谱仪碰撞池的研究现状与进展[J].现代科学仪器,2013,(3):7-13,7.基金项目
国家重大科学仪器设备开发专项(2011YQ060084),国家重大科学仪器设备开发专项(2011YQ130043) (2011YQ060084)