中国实用妇科与产科杂志2013,Vol.29Issue(7):579-583,5.
宫颈炎康栓治疗宫颈高危型人乳头瘤病毒感染疗效观察
Clinical effects of gongjingyankang suppository for the treatment of high-risk HPV infection
侯萌 1安瑞芳 1吴静 2辛晓燕 3陈丽宏 4李娜 1朱广侠 1崔绪琴 1苟文丽1
作者信息
- 1. 西安交通大学医学院第一附属医院妇产科,陕西西安710061
- 2. 西安交通大学第二附属医院妇产科,陕西西安710004
- 3. 第四军医大学西京医院妇产科,陕西西安710032
- 4. 陕西省人民医院妇产科,陕西西安710068
- 折叠
摘要
Abstract
Objective To study the effects of Chinese medicine gongjingyankang suppository for the treatment of high-risk HPV infection and cervical erosion change.Methods 205 cases which had been diagnosed as genital tract high-risk HPV virus infections from November 2011 to November 2012 were selected from the gynecological clinic of the following hospitals:the First Hospital and the Second Hospital of Xi'an Jiaotong University,the Fourth Military Medical University Xijing Hospital and Shanxi People's Hospital.These cases have been ruled out CIN and cervical cancer by cervical TCT,vaginal lens check,and cervical biopsy if necessary.The treatment group,which included 105 cases at first,consists of 102 cases using gongjingyankang for 2 months.The other 100 cases in the control group are observed only.Two months later,cervical secretion HPV examination,pelvic examination,leucorrhea routine examination,cervical TCT,vaginal lens check were taken again to make sure the drug effects.Results In the treatment group,the high-risk HPV negative rate is 34.3% and 45.1% respectively in 1 and 2 months after treatment.Among the cases of less than 35 year-old ones and older than 35 year-old ones,high-risk HPV negative rate has no statistical difference.After treatment,the HPV subtypes with higher negative rate include HPV56 (71.5%),HPV39 (72.8%),HPV18 (71.5%),HPV31 (68.5%) and HPV59 (66.7%).Gongjingyankang is effective to cervical erosion change.The total effective rate is 54.4%.We accidentally find that gongjingyankang is effective to genital tract mycoplasma infection.The total effective rate is 100.0%.Conclusion Chinese medicine gongjingyankang can effectively turn high-risk HPV infection from positive to negative,improve the cervical erosion change,and may be effective to genital tract mycoplasma infection.关键词
宫颈炎康栓/高危人乳头瘤病毒亚型/感染/宫颈糜烂样改变/宫颈癌Key words
gongjingyankang suppository/ high-risk HPV types /infection/ cervical erosion change/ cervical cancer=分类
医药卫生引用本文复制引用
侯萌,安瑞芳,吴静,辛晓燕,陈丽宏,李娜,朱广侠,崔绪琴,苟文丽..宫颈炎康栓治疗宫颈高危型人乳头瘤病毒感染疗效观察[J].中国实用妇科与产科杂志,2013,29(7):579-583,5.