高等学校化学学报2013，Vol.34Issue(6)：1416-1422,7.DOI:10.7503/cjcu20120972s
含有单取代嘧啶的新型磺酰脲类化合物的设计、合成及除草活性
Design, Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Monosubstituted Pyrimidine Moiety
摘要
Abstract
Sulfonylureas,a unique group of herbicides,were extensively applied to controlling a range of weeds in a variety of crops and vegetables.In order to find efficient sulfonylurea herbicides,the title compounds were designed by introducing monosubstituted pyrimidinamines into some well-known sulfonylurea skeletons.A series of sulfonylurea compounds were synthesized and characterized by 1H NMR and HRMS.Herbicidal activities and IC50 values of the title compounds were determined by Pot plant test and Petri dish test against Brassica napus,Amaranthus retroflexus,Echinochloa crusgalli and Digitaria adscendens.Some compounds exhibited herbicidal activities.Compounds 7b and 7d possessed significant inhibition effects against Brassica napus and Amaranthus retroflexus.Further structural modification of novel sulfonylureas containing monosubstituted pyrimidine moiety will be required for improving efficacy against weeds in our lab.关键词
磺酰脲/单取代嘧啶/除草活性Key words
Sulfonylurea/ Monosubstituted pyrimidine/ Herbicidal activity分类
化学化工引用本文复制引用
潘里,刘卓,陈有为,李永红,李正名..含有单取代嘧啶的新型磺酰脲类化合物的设计、合成及除草活性[J].高等学校化学学报,2013,34(6):1416-1422,7.基金项目
国家自然科学基金(批准号:21272129)、国家"九七三"计划项目(批准号:2010CB126106)和国家科技攻关计划项目(批准号:2011BAE06B05)资助. （批准号:21272129）
