南京医科大学学报(自然科学版)2013,Vol.33Issue(5):665-668,4.DOI:10.7655/NYDXBNS20130521
2008~2011年鲍曼不动杆菌科室分布和耐药性变迁分析
Changes of department distribution and antimicrobial agents resistance among Acinetobacter baumannii isolated during 2008 to 2011
摘要
Abstract
Objective:For guiding the clinical therapy,we sought to analyze the changing of department distribution and the resistance of Acinetobacter baumannii from the First Affiliated Hospital of NJMU during 2008 to 2011 Methods:The bacteria were identified by VITEK2 identification system or API bacterial identification strip.Antimicrobial susceptibility testing were carried out by the disc diffusion method (Kirby-Bauer method).Data analyses were performed by Whonet 5.6 software.Results:Acinetobacter baumannii ranked the highest proportion (80.0%) in sputum samples.The bacteria was detected in some clinical departments,including geriatrics,ICU,emergency department,respiratory and neurosurgery.The resistance rates to cefoperazone/sulbactam,imipenem and meropenem among A cinetobacter baumannii in 2008 were 12.0%,14.8% and 23.3%,respectively;while the resistance rates in 2011 increased to 67.4%,90.8% and 91.1%,respectively.Conclusion:We found that the resistance rates of many clinical used antimicrobial agents significantly increased in Acinetobacter baumannii isolates.We should pay attention to the antimicrobial resistance monitoring and control its spread.关键词
鲍曼不动杆菌/药敏试验/耐药性监测Key words
Acinetobacter baumannii/ susceptibility testing/ resistance monitoring分类
医药卫生引用本文复制引用
蒋秀园,王珏,徐婷,顾兵,文怡,刘根焰,梅亚宁..2008~2011年鲍曼不动杆菌科室分布和耐药性变迁分析[J].南京医科大学学报(自然科学版),2013,33(5):665-668,4.基金项目
国家自然科学基金(81000754) (81000754)