中国兽医科学2013，Vol.43Issue(6)：629-633,5.
不同日龄海兰白鸡眼结膜相关淋巴组织中T淋巴细胞的分布变化规律
Distribution changes of T lymphocyte in conjunctiva-associated lymphoid tissue of Hy-line Variety White chicken at different ages
摘要
Abstract
The aim of this study was to investigate the immune state of conjunctiva-associated lymphoid tissues(CALT) of chicken in different ages.With lower eyelids of Hy-line Variety White chicken at different ages,the location,distribution changes and quantity of CD3+,CD4+ and CD8+ T lymphocytes in CALT were studied using immunohistochemistry staining.The results showed that both CD3+ and CD8+ T lymphocytes appeared firstly in CALT at 1-day-old,while CD4+ cells appeared at 4-day-old.T lymphocytes were distributed mainly in the middle and underneath of mucous layer before 7-day-old.CD3+ and CD8+ cells were distributed in the mucosal epithelium and lamina propria after 14-day-old,while CD4+ cells were predominantly present in the peripheral area of the follicle and the inter-follicular areas.The amount of T lymphocytes increased gradually and a rapid increase occured at 14-and 21-day-old and then remained stable after a summit at 27-day-old.The results revealed that the immune functions of CALT in chickens gradually enhanced with the increase of age,and the immune function reached the mature level basically at 27-day-old.关键词
鸡/眼结膜相关淋巴组织/T淋巴细胞/发育Key words
chicken/ conjunctiva-associated lymphoid tissue / T lymphocyte/ development分类
农业科技引用本文复制引用
金唯,张英楠,杨树宝,栾维民,马馨,彭琪,董红艳,马金萍,钱爱东..不同日龄海兰白鸡眼结膜相关淋巴组织中T淋巴细胞的分布变化规律[J].中国兽医科学,2013,43(6):629-633,5.基金项目
国家自然科学基金项目(30901065) （30901065）
吉林省科技发展计划项目(201205059) （201205059）
