山东中医药大学学报2013,Vol.37Issue(4):289-291,3.
隔药灸脐法对脾虚型肠易激综合征患者脑肠肽的影响
Effect of herb-partitioned moxibustion at navel on serum ghrelin of irritable bowel syndrome patients with spleen deficiency pattern
摘要
Abstract
Objective:To explore the effect of herb-partitioned moxibustion at navel(Shenque,CV8) on serum ghrelin in irritable bowel syndrome(IBS) patients with spleen deficiency pattern.Methods:Total 210 patients were randomly assigned into 3 groups.One group was treated with herb-partitioned moxibustion at the navel(n=75),the second group was treated with farina-partitioned moxibustion at the navel(n=75) and the third group was treated with western medicine(n=60).All patients were treated for 4 weeks.The content of serum substance P(SP),vascoactive intestinal peptide(VIP) and 5-hydroxytryptamine(5-HT) were detected by ELISA before and after treatment.Results:After treatment,the content of serum SP,VIP and 5-HT of herb-partitioned moxibustion group reduced,compared with those before treatment,there were significant difference(P<0.05).However,there were no significant differences of serum SP,VIP and 5-HT between the three groups.Conclusion:Herb-partitioned moxibustion at navel could reduce the content of serum SP,VIP and 5-HT and improve the bowel function of IBS patients.关键词
肠易激综合征/隔药灸脐/P物质/血管活性肠肽/5-羟色胺/临床研究Key words
irritable bowel syndrome/herb-partitioned moxibustion at navel/substance P/vasoactive intestinal peptide/5-hydroxytryptamine / clinical study分类
医药卫生引用本文复制引用
刘骁,郭刚,马玉侠,刘存志,高树中..隔药灸脐法对脾虚型肠易激综合征患者脑肠肽的影响[J].山东中医药大学学报,2013,37(4):289-291,3.基金项目
国家重点基础研究发展计划(973)课题(编号:2007CB512703) (973)
国家自然基金面上项目(编号:30973789) (编号:30973789)