摘要
Abstract
OBJECTIVE:To observe the clinical efficacy of Lianhua qingwen capsule in the treatment of pediatric epidemic influenza.METHODS:128 cases of pediatric epidemic influenza were randomly divided into observation group and control group,with 64 cases in each group.Observation group was given Lianhua qingwen capsule,0.70 mg each time,3 times a day,and control group was given Shuanghuanglian oral liquid 10 ml,twice a day.2 groups were treated for 7 days.The flu symptoms score,defervescence effect,dinical efficacy,average healing time,average defervescence time and ADR were compared between 2 groups.RESULTS:After treatment,the clinical total effective rate of observation group was 93.75％,which was higher than 90.63％ in control group,but no difference was found between 2 groups(P＞0.05).The total effective rate of cooling was 85.94％ in observation group and 62.50％ in control group； there was significant difference between 2 groups(P＜0.05)； the average healing time of observation group was (49.38 ± 12.88) h and the average defervescence time was (20.68 ± 14.12) h,which were significantly lower than those of control group [(53.96 ± 11.79)h,(25.77 ± 13.96)h,P＜0.05].The headache,sore throat,muscle pain score of observation group was significantly lower than those of control group after treatment,the difference was statistically significant (P＜0.05) in 2 groups.No serious adverse drug reactions was found in 2 groups.CONCLUSIONS:Lianhua qingwen capsule is effective in the treatment of pediatric epidemic influenza,and relieve headache,sore throat,muscle pain and other symptoms with less ADR and good safety.关键词
流行性感冒/连花清瘟胶囊/疗效/安全性Key words
Epidemic influenza/ Lianhua qingwen capsule/ Clinical efficacy/ Safety分类
医药卫生
