中国药房2013，Vol.24Issue(28)：2646-2648,3.DOI:10.6039/j.issn.1001-0408.2013.28.19
喷他佐辛复合丙泊酚静脉麻醉用于经内窥镜逆行胰胆管造影的临床观察
Clinical Observation of the Application of Pentazocine Combined with Propofol Anesthesia in ERCP
杨烨 1李雯 2曹莹 2韩明 3王旭浩3
作者信息
- 1. 贵州省骨科医院麻醉科,贵阳550007
- 2. 贵阳医学院附属医院麻醉科,贵阳550004
- 3. 贵阳医学院附属医院肝胆外科,贵阳550004
- 折叠
摘要
Abstract
OBJECTIVE:To investigate the anaesthetic effect of pentazocine combined with propofol anesthesia in ERCP.METHODS:100 patients undergoing ERCP were randomly assigned to 5 groups.Group C was given fentanyl 1 μg/kg； group P (group P1-4) was given pentazocine 0.4、0.6、0.8、1.0 mg/kg.Each group was induced by intravenous injection of propofol 1.0-1.5 mg/kg,followed by pumping 3-6 mg/(kg· h).Anaesthetic effect,intraoperative vital signs,respiratory cycle inhibition,VAS score,postoperative nausea,vomiting and other ADRs were all observed,and the dose of propofol,the time needed for awakening,directive force recovery time,etc.were all recorded.RESULTS:The anaesthetic effects of group P2,P3 and P4 were better than others,but the adverse events of group P2 and P3 was less than other groups； the time needed for awakening of group P4 was the longest,and the dose of propofol in group C was the largest.There was statistical significance (P＜0.05).VAS score of group P1-4 was lower than group C (P＜0.05).Anesthesia induction time,surgeny knowing,ADRs was no statistical significance(P＞0.05).CONCLUSIONS:Pentazocine 0.6-0.8 mg/kg combined with propofol is optimal scheme for anesthesia during ERCP,and can reduce adverse events,relieve postoperative pail and decrease the dose of propofol.关键词
喷他佐辛/丙泊酚/经内窥镜逆行胰胆管造影/临床观察/剂量Key words
Pentazocine/ Propofol/ ERCP/ Clinical observation/ Dose分类
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杨烨,李雯,曹莹,韩明,王旭浩..喷他佐辛复合丙泊酚静脉麻醉用于经内窥镜逆行胰胆管造影的临床观察[J].中国药房,2013,24(28):2646-2648,3.
