中国药房2013，Vol.24Issue(28)：2676-2678,3.DOI:10.6039/j.issn.1001-0408.2013.28.29
一测多评法测定清热解毒口服液中4种成分的含量
Content Determination of 4 Components in Qingre Jiedu Oral Liquid by QAMS
摘要
Abstract
OBJECTIVE:To develop QAMS method for the content determination of 4 active components in Qingre jiedu oral liquid.METHODS:Using baicalin as intemal standard,relative correction factors of baicalin to caffeotannic acid,forsythin and jasminoidin were established by HPLC and calculated to achieve QAMS.The contents of 4 components in the samples were determined with the external standard method.The accuracy of the method was validated by compare the results of 2 method.RESULTS:Established correction factors showed sound reproducibility.No significant differences between the quantitative results of QAMS method and external standard method were observe.CONCLUSIONS:Using baicalin,caffeotannic acid,forsythin and jasminoidin as index,QAMS is feasible for quality control of Qingre jiedu oral liquid.关键词
一测多评法/外标法/高效液相色谱法/校正因子/清热解毒口服液/含量测定Key words
QAMS/ External method/ HPLC/ Correction factor/ Qingre jiedu oral liquid/ Content determination分类
医药卫生引用本文复制引用
张振巍,张娜娜,白丹丹,于秋影,石磊,李月梅..一测多评法测定清热解毒口服液中4种成分的含量[J].中国药房,2013,24(28):2676-2678,3.基金项目
济南军区后勤科研计划项目(No.CJN10L067) （No.CJN10L067）
