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胃肠神经内分泌肿瘤和胰腺神经内分泌肿瘤的区别

李晓青 钱家鸣

临床肝胆病杂志2013,Vol.29Issue(7):492-495,4.
临床肝胆病杂志2013,Vol.29Issue(7):492-495,4.DOI:10.3969/j.issn.1001-5256.2013.07.004

胃肠神经内分泌肿瘤和胰腺神经内分泌肿瘤的区别

Differentiation between gastrointestinal neuroendocrine tumors and pancreatic neuroendocrine tumors

李晓青 1钱家鸣1

作者信息

  • 1. 北京协和医院消化内科,北京100730
  • 折叠

摘要

Abstract

Gastrointestinal and pancreatic neuroendocrine tumors (GEP-NETs) are mainly derived from the neuroendocrine cells of the gastrointestinal-pancreatic system,which express cell type-specific peptide hormones and general markers (synaptic vesicle proteins and chromogranin A).GEP-NETs have the following characteristics:they are rarely seen in the clinical setting; the tumor sizes are usually small (< 1 cm) ; tumors grow slowly (for months or years),with several stages of development,and they probably have no symptoms for years; metastases often occur before onset of symptoms,with the liver and bones commonly affected,and the tumor sizes are larger than 2 cm at this time.Thus,GEP-NETs are often misdiagnosed; the diagnostic process is complex,not only relying on clinical manifestations,but also advanced laboratory and scanning means.Moreover,gastrointestinal NETs and pancreatic NETs differ in clinical manifestations,diagnosis,and treatment,and clinicians need to pay more attention to differentiation between them.

关键词

神经内分泌瘤/胃肠肿瘤/胰腺肿瘤

Key words

neuroendocrine tumors / gastrointestinal neoplasms/ pancreatic neoplasms

分类

医药卫生

引用本文复制引用

李晓青,钱家鸣..胃肠神经内分泌肿瘤和胰腺神经内分泌肿瘤的区别[J].临床肝胆病杂志,2013,29(7):492-495,4.

临床肝胆病杂志

OACSTPCD

1001-5256

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