临床肝胆病杂志2013,Vol.29Issue(7):550-553,4.DOI:10.3969/j.issn.1001-5256.2013.07.020
肝癌细胞侵犯微血管的临床相关因素及分子标志物的研究进展
Research progress in related clinical factors and molecular biomarkers for microvascular invasion in hepatocellular carcinoma
摘要
Abstract
Microvascular invasion (MVI) is considered an important influential factor for postoperative recurrence and prognosis of hepatocellular carcinoma (HCC).Little attention has been given to the treatment targeting MVI,and the preoperative identification of MVI remains an unsolved challenge.This paper reviews the research progress in related clinical factors and molecular biomarkers for MVI in HCC and summarizes the confirmed factors closely associated with MVI,such as tumor size,tumor number,tumor differentiation,des-γ-carboxy prothrombin,and alpha-fetal protein.Seeking a new specific serum marker for MVI is still the research orientation in this area.关键词
肝肿瘤/微血管侵犯/生物学标记Key words
liver neoplasms/ micro vascular invasion/ biological markers分类
医药卫生引用本文复制引用
金赟,李江涛..肝癌细胞侵犯微血管的临床相关因素及分子标志物的研究进展[J].临床肝胆病杂志,2013,29(7):550-553,4.基金项目
国家自然科学基金资助项目(81272673) (81272673)