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肝癌细胞侵犯微血管的临床相关因素及分子标志物的研究进展

金赟 李江涛

临床肝胆病杂志2013,Vol.29Issue(7):550-553,4.
临床肝胆病杂志2013,Vol.29Issue(7):550-553,4.DOI:10.3969/j.issn.1001-5256.2013.07.020

肝癌细胞侵犯微血管的临床相关因素及分子标志物的研究进展

Research progress in related clinical factors and molecular biomarkers for microvascular invasion in hepatocellular carcinoma

金赟 1李江涛1

作者信息

  • 1. 浙江大学医学院附属第二医院普外科,杭州310009
  • 折叠

摘要

Abstract

Microvascular invasion (MVI) is considered an important influential factor for postoperative recurrence and prognosis of hepatocellular carcinoma (HCC).Little attention has been given to the treatment targeting MVI,and the preoperative identification of MVI remains an unsolved challenge.This paper reviews the research progress in related clinical factors and molecular biomarkers for MVI in HCC and summarizes the confirmed factors closely associated with MVI,such as tumor size,tumor number,tumor differentiation,des-γ-carboxy prothrombin,and alpha-fetal protein.Seeking a new specific serum marker for MVI is still the research orientation in this area.

关键词

肝肿瘤/微血管侵犯/生物学标记

Key words

liver neoplasms/ micro vascular invasion/ biological markers

分类

医药卫生

引用本文复制引用

金赟,李江涛..肝癌细胞侵犯微血管的临床相关因素及分子标志物的研究进展[J].临床肝胆病杂志,2013,29(7):550-553,4.

基金项目

国家自然科学基金资助项目(81272673) (81272673)

临床肝胆病杂志

OACSTPCD

1001-5256

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