南京医科大学学报(自然科学版)2013,Vol.33Issue(8):1152-1154,3.DOI:10.7655/NYDXBNS20130826
胸水中腺癌细胞和反应性间皮细胞的计算机判别
Computer discrimination between adenocarcinoma cells and reactive mesothelial cells in hydrothorax
摘要
Abstract
Objective:To explore the method of computer discriminant on adenocarcinoma cells (ACC) and reactive mesothelial cells (RMC) amd establish the foundation on computer diagnosis for ACC in hydrothorax.Methods:Totally764 ACC of 44 cases and 709 RMC of 39 cases were collected from hydrothorax smears.Technique of computer image analysis was applied to test chromatics and morphological structure parameters of above cells.Approximately 80% cells were randomly selected as train group,and residual 20% cells as test group,the stepwise discriminant analysis was used in train group to establish the discriminant function,and the discriminant effects of function in test group were evaluated.Results:Stepwise discriminant showed that Rp,Bp,Rm,Bn,dmaj,c、dmin,c、An、D-n、Cn entered discriminant function,and its coincidence rate was 84.5%.The discriminant effect was significantly better than that in functions individually based on chromatics and morphological structure parameters (P < 0.05).Conclusion:The function combined with chromatics and morphological structure parameters has good discriminant effect,and it provides the analysis path of computer quantitative diagnosis for ACC in hydrothorax.关键词
胸水/腺癌细胞/反应性间皮细胞/色度学/形态结构/计算机判别Key words
hydrothorax/ adenocarcinoma cell/ reactive mesothelial cell/ chromatics/ morphological structure/ computer discriminant分类
医药卫生引用本文复制引用
蓝永洪,牛海艳,饶朗毓,江朝娜,林世珍,杨智,符碧薇..胸水中腺癌细胞和反应性间皮细胞的计算机判别[J].南京医科大学学报(自然科学版),2013,33(8):1152-1154,3.基金项目
海南省自然科学基金资助(812194) (812194)