实用肿瘤杂志2013，Vol.28Issue(4)：374-377,4.
椎板减压联合射频消融辅助椎体成形术治疗肺癌脊柱转移的临床研究
Posterior laminectomy and vertebroplasty combined with radiofrequency ablation in spinal metastases from lung cancer
韩秀鑫 1王国文 1张超 1滕胜 1马育林 1多健 1杨吉龙1
作者信息
- 1. 天津医科大学附属肿瘤医院骨与软组织肿瘤科,天津市肿瘤防治重点实验室,天津300060
- 折叠
摘要
Abstract
Objective To investigate the safety and efficacy of laminectomy and vertebroplasty with radiofrequency ablation in spinal metastases from lung cancer.Methods Clinical data of 11 cases with spinal metastases from lung cancer were retrospectively analyzed.All received posterior laminectomy to relieve the compression of spinal cord,and vertebroplasty combined with radiofrequency ablation (RFA) was performed,followed by instrumented fixation.The operative time,the blood loss and the rate of bone cement leakage were analyzed.The pain levels before and 1 month after operation were assessed by visual analogue scale (VAS) ; the neurological deficit was evaluated by Frankel grade and the functional impairment was classified by Karnofsky score.The quality of life was assessed by EORTC QLQ-C30 questionnaire.Results The mean operative time was (150 ± 99.21) min.The blood loss was (410.00 ± 102.23) mL.The rate of bone cement leakage was 27.3％.The VAS at 1 month after operation was improved compared to preoperative VAS (P ＜ 0.01).The rate of Frankel grade D or E in patients was increased from 45.5 ％ to 81.8 ％ after operation ; the rate of KPS score (80 ～ 100) increased from 36.4％ to 72.7％ after operation,including 5 out of 9 patients whose sphincteric dysfunction was improved.The EORTC QLQ-C30 scores were 84.09 ± 9.48 and 54.64 ± 15.17 before and after operation,respectively (P ＜ 0.01).Conclusion Posterior laminectomy and vertebroplasty combined with radiofrequency ablation is safe and effective.It can release pain,improve function and quality of life in lung cancer patients with spinal metastases.关键词
肺肿瘤/并发症/脊椎肿瘤/继发性/椎体成形术/方法/导管消融术/方法/综合疗法/回顾性研究Key words
lung neoplasms/complications/spinal neoplasms/secondary/vertebroplasty/methods/catheter ablation/methods/combined modality therapy/retrospective studies分类
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韩秀鑫,王国文,张超,滕胜,马育林,多健,杨吉龙..椎板减压联合射频消融辅助椎体成形术治疗肺癌脊柱转移的临床研究[J].实用肿瘤杂志,2013,28(4):374-377,4.
