西北国防医学杂志2013，Vol.34Issue(4)：304-306,3.
替米沙坦联合胺碘酮治疗慢性心力衰竭合并阵发性房颤的临床观察
Clinical efficacy of telmisartan combined with amiodarone in the treatment of chronic heart failure with paroxysmal atrial fibrillation
摘要
Abstract
Objective:To investigate the effect of telmisartan combined with amiodarone in the treatment of chronic heart failure with paroxysmal atrial fibrillation.Methods:167 patients of chronic heart failure with paroxysmal atrial fibrillation were enrolled in this study,amiodarone was used to maintain sinus rhythm.All of the patients were divided into the treatment group and the control group according to the combined treatment of telmisartan.After one year's treatment,the hospitalization for heart failure rate,left ventricular ejection fraction,left atrial diameter,the rate of sinus rhythm maintenance and the rate of permanence atrial fibrillation were observed and analysed.Results:The rate of recurrence of atrial fibrillation and the incidence of chronic atrial fibrillation in the treatment group was significantly lower than that of the control group; sinus rhythm maintenance rate was significantly higher than that of the control group,left atrial diameter was significantly reduced compared with the control group,the rate of hospitalization for heart failure was significantly lower than that of the control group (P ＜ 0.05).There was no significant difference in adverse reactions between the two groups (thyroid dysfunction,abnormal liver function,pulmonary fibrosis and hypotension,P ＞ 0.05).Conclusion:The treatment of telmisartan combined with amiodarone for chronic heart failure with paroxysmal atrial could maintain sinus rhythm,reduce the rate of hospitalization for heart failure,and has a better effect on myocardial remodeling with good security.关键词
慢性心力衰竭/替米沙坦/胺碘酮/阵发性房颤Key words
Chronic heart failure / Telmisartan / Amiodarone/ Paroxysmal atrial fibrillation分类
医药卫生引用本文复制引用
李小明,王霞..替米沙坦联合胺碘酮治疗慢性心力衰竭合并阵发性房颤的临床观察[J].西北国防医学杂志,2013,34(4):304-306,3.基金项目
国家自然科学基金资助项目(30770823) （30770823）
