中国普通外科杂志2013,Vol.22Issue(7):835-840,6.DOI:10.7659/j.issn.1005-6947.2013.07.004
射频消融对比手术切除治疗孤立性结直肠癌肝转移肿瘤的Meta分析
Radiofrequency ablation versus hepatic resection for solitary colorectal liver metastasis: a Meta-analysis
许浩 1王家胜 1杨恒 1刘洋 1杨强1
作者信息
- 1. 重庆医科大学附属永川医院普通外科,重庆402160
- 折叠
摘要
Abstract
Objective:To compare the therapeutic efficacies between radiofrequency ablation (RFA) and hepatic resection for solitary colorectal liver metastasis.Methods:The controlled clinical trials concerning RFA and hepatic resection for treatment of solitary colorectal liver metastasis were collected through literature retrieval from several native and foreign online databases.The quality of the include studies was assessed according to the Cochrane systematic review method,and data analysis was conducted by using RevMan 5.0 software.Results:Nine studies were finally included,with a total of 1 259 patients,of whom,440 cases underwent RFA and 819 cases were subjected to surgical resection.The results of Meta-analysis demonstrated that the S-year overall survival rate was lower,and the overall recurrence and local recurrence rate was higher in patients undergoing RFA than that in patients receiving surgical resection (P=0.02,P=0.01,P=0.003); there was no obvious difference in S-year overall survival rate after operation between patients undergoing RFA and hepatic resection when the tumor diameter was less than 3 cm (P=0.43).Conclusion:Hepatic resection has a better efficacy than that of RFA for solitary colorectal liver metastasis,but RFA could be considered when tumor diameter is less than 3 cm.关键词
肝肿瘤/结直肠肿瘤/肝切除术/射频消融术/Meta分析Key words
Liver Neoplasms/ Colorectal Neoplasms/ Hepatectomy/ Radiofrequency Ablation/ Meta-Analysis分类
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许浩,王家胜,杨恒,刘洋,杨强..射频消融对比手术切除治疗孤立性结直肠癌肝转移肿瘤的Meta分析[J].中国普通外科杂志,2013,22(7):835-840,6.