中药材2013，Vol.36Issue(5)：771-775,5.
红芪黄酮对肺间质纤维化模型大鼠肺功能的影响
Effect of Flavonoids from Hedysari Radix on Pulmonary Functions of Pulmonary Fibrosis Rat
摘要
Abstract
Objective:To study the effect of flavonoids from Hedysari Radix on pulmonary functions of pulmonary fibrosis rat and its mechanism.Methods:72 Wistar rats were randomly divided into 6 groups:blank control group,model group,prednisone group,Hedysari Radix flavonoids low,medium and high dosage group.The rat model was established by propelling bleomycin into bronchial tree through endotracheal intubation with laryngoscope.The pulmonary fanctions were measured.Results:Hedysari Radix flavonoids could normalize the pulmonary functions of rats with bleomycin-induced pulmonary fibrosis.Conclusion:Hedysari Radix flavonoids can inhibit the process of pulmonary fibrosis.关键词
红芪黄铜/肺纤维化/大鼠模型/肺功能Key words
Hedysari Radix flavonoids/ Pulmonary fibrosis/ Rat models / Pulmonary functions分类
医药卫生引用本文复制引用
李娟,蔺兴遥,李金田,张毅,李雪燕,刘永琦,景明,孙少伯,苏韫..红芪黄酮对肺间质纤维化模型大鼠肺功能的影响[J].中药材,2013,36(5):771-775,5.基金项目
国家自然科学基金地区科学基金(30960037/C020409) （30960037/C020409）
2004年教育部春晖计划项目(Z2004-1-620039) （Z2004-1-620039）
