东南大学学报（自然科学版）2013，Vol.43Issue(4)：724-728,5.DOI:10.3969/j.issn.1001-0505.2013.04.010
λ-DNA通过纳米通道产生电流信号的1/f噪声分析
1/f noise analysis of current signals generated by λ-DNA translocation through nanochannel
摘要
Abstract
The current signals generated by λ-DNA translocation through nanochannels were collected by using the patch clamp.The influences of voltage,channel geometry shape and size,salt concentration and channel materials on the l/f noise were analyzed.The results show that the 1/f noise in nanochannel is caused by the comprehensive action of the ions in the solution and the surface charge of the nanochannel.As for the silicon nitride (SiN) nanochannel,a charge local congestion phenomenon occurs in the nanochannel when the absolute value of the voltage is increased to some extent,inducing the increase of the local resistance and the power of 1/f noise.The diameter of SiN nanochannel has little effect on the 1/f noise of the detected ionic signals.Compared with the SiN nanochannel,the grapheme nanochannel has larger noise because of its bigger structure of capacitance and higher carrier mobility.The results can help to identify the current signals with high signalto-noise ratio generated by λ-DNA translocation through nanochannels.关键词
纳米通道/λ-DNA/1/f噪声Key words
nanochannel/λ-DNA/1/f noise分类
机械制造引用本文复制引用
顾兴中,刘磊,王霏,倪中华..λ-DNA通过纳米通道产生电流信号的1/f噪声分析[J].东南大学学报（自然科学版）,2013,43(4):724-728,5.基金项目
国家重点基础研究发展计划(973计划)资助项目(2011CB707601,2011CB707605)、江苏省自然科学基金资助项目(BK2010398,BK2011037). （973计划）
