广东药学院学报2013，Vol.29Issue(3)：322-325,4.DOI:10.3969/j.issn.1006-8783.2013.03.026
DMPP对于鸡胚血管形成的抑制作用
Inhibitory effect of DMPP in the angiogenesis of chick embryo
摘要
Abstract
Objective To investigate the role of 1,1-dimethyl-4-phenylpiperazinium (DMPP)in the angiogenesis of early chick embryo.Methods The chicken chorioallantoic membrane (CAM)and yolk sac membrane (YSM) were treated with 50 μg/mL DMPP.The angiogenesis of CAM was observed visually.The vascular density and growth rate of YSM were examined by microscopy.Results DMPP obviously suppressed the angiogenesis of CAM and decreased the vascular density and growth rate of YSM.Conclusion DMPP exhibits an inhibitory effect on the angiogenesis of chicken embryo.关键词
DMPP/鸡胚绒毛尿囊膜/鸡胚绒毛卵黄囊膜/血管形成Key words
DMPP/ chicken chorioallantoic membrane/ yolk sac membrane/ angiogenesis分类
药学引用本文复制引用
周秦,何晓东,亓翠玲,李江超,郭四美,叶杰,韩露,王丽京..DMPP对于鸡胚血管形成的抑制作用[J].广东药学院学报,2013,29(3):322-325,4.基金项目
国家自然科学基金面上项目(31271455) （31271455）
