国际医学放射学杂志2013，Vol.36Issue(4)：331-335,339,6.DOI:10.3874/j.issn.1674-1897.2013.04.Z0404
乳腺癌X线征象与p53、Ki-67表达相关性的研究进展
Progress of the correlation study between mammographic appearances and expression of p53,Ki-67 in patients with breast cancer
柳杰1
作者信息
- 1. 300060,天津医科大学附属肿瘤医院乳腺影像诊断科,乳腺癌防治教育部重点实验室,天津市肿瘤防治重点实验室
- 折叠
摘要
Abstract
Breast cancer is one of the most common female malignant tumors.The occurrence and development of breast cancer are often accompanied by abnormal gene expression.It has been well accepted that p53,Ki-67 are the commonly used biological indicators for clinical endocrine therapy and prognosis prediction.The oncogene expression reflects the malignant biological behavior of breast cancer from different perspectives.Those aggressive behaviors cause a variety of changes in histopathology and thus in imaging.Therefore,the imaging features of breast cancer may indirectly demonstrate the status of p53,Ki-67.Until now,because of its facility,low cost and high accuracy,mammography is still the preferred method in breast cancer screening and diagnosis.The relationship of mammographic appearances and gene expression in patients with breast cancer has potential clinical value in preoperative evaluation and planning of non-surgical treatment for those who are not able to perform immunohistochemistry.关键词
乳腺癌/乳腺X线征象/p53/Ki-67Key words
Breast cancer/ Mammographic appearances/ p53/ Ki-67引用本文复制引用
柳杰..乳腺癌X线征象与p53、Ki-67表达相关性的研究进展[J].国际医学放射学杂志,2013,36(4):331-335,339,6.
