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抗菌肽在皮肤病治疗中的研究进展

沈亮

基础医学与临床2013,Vol.33Issue(8):1063-1066,4.
基础医学与临床2013,Vol.33Issue(8):1063-1066,4.

抗菌肽在皮肤病治疗中的研究进展

Recent advances of antimicrobial peptides in dermatology

沈亮1

作者信息

  • 1. 德州学院生物系功能大分子山东省重点实验室,山东德州253023
  • 折叠

摘要

Abstract

Antimicrobial peptides have been shown to serve as a first-line defense mechanism against potential pathogens in the skin.The antibacterial mechanism of cationic antimicrobial peptides in skin disease process has been extensively studied,but anionic antimicrobial peptides is relatively unknown.The role of antimicrobial peptides in epidermal immunity and low predilection for developing bacterial resistance has been studied extensively thus far,the potential health benefits of the use of synthetic bioactive peptides is promising in dermatological disease.But some technical obstacles must be overcome before they can be successfully translated into clinical application.

关键词

生物活性肽/抗菌肽/皮肤病/治疗

Key words

bioactive peptides/ antimicrobial peptides / dermatology/ therapeutics

分类

医药卫生

引用本文复制引用

沈亮..抗菌肽在皮肤病治疗中的研究进展[J].基础医学与临床,2013,33(8):1063-1066,4.

基金项目

山东省科技攻关计划项目(2011YD10008) (2011YD10008)

山东省星火计划(2011XH13005)德州市科技发展计划项目(2011B04) (2011XH13005)

基础医学与临床

OA北大核心CSCDCSTPCD

1001-6325

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