山西医科大学学报2013，Vol.44Issue(7)：573-575,3.DOI:10.3969/J.ISSN.1007-6611.2013.07.018
单剂量右美托咪啶对七氟烷吸入麻醉苏醒期躁动的影响
Effects of dexmedetomidine on agitation in recovery period after sevoflurane anesthesia
鲁会卿 1李宏 1陈宁1
作者信息
- 1. 武警后勤学院附属医院麻醉科,天津300162
- 折叠
摘要
Abstract
Objective To explore the effects of dexmedetomidine on emergence agitation after sevoflurane anesthesia.Methods Sixty ASA Ⅰ-Ⅱ patients undergoing elective abdominal operation under sevoflurane anesthesia were randomized into 2 groups (n =30).All patients received infusion of remifentanil and inhalation of 2％-3％ sevoflurane.The patients were given intravenously 0.5 μg/kg dexmedetomidine in dexmedetomidine group 30 min before the end of surgery and 0.9％ NaCl in control group.The same observer in postanesthesia care unit(PACU) was blinded to treatment groups.Hemodynamic parameters and emergence agitation was evaluated at different time points.Results Heart rate and mean arterial pressure were significantly lower in dexmedetomidine group than in control group (P ＜ 0.05).The incidence of agitation was also significantly lower in dexmedetomidine group than in control group (P ＜ 0.05).Conclusion Single dose of 0.5 μg/kg dexmedetomidine can promote the hemodynamic stability during extubation and reduce the incidence of agitation in recovery period after sevoflurane anesthesia.关键词
右美托咪啶/七氟烷/苏醒期/躁动Key words
dexmedetomidine / sevoflurane / recovery period/ agitation分类
医药卫生引用本文复制引用
鲁会卿,李宏,陈宁..单剂量右美托咪啶对七氟烷吸入麻醉苏醒期躁动的影响[J].山西医科大学学报,2013,44(7):573-575,3.
