实用妇产科杂志2013，Vol.29Issue(7)：536-538,3.
来曲唑微刺激方案和短方案对卵巢低反应助孕的临床研究
The Clinical Research of Application about Short Programs and Mini-stimulation Protocols of Letrozole in the Assisted Reproduction Patient of Poor Ovarian Response
林敏 1刘林丽 1陈华 1吕杰强1
作者信息
- 1. 温州医学院附属第二医院,浙江温州 325027
- 折叠
摘要
Abstract
Objective:To explore the effect of short programs and mini-stimulation protocols of letrozole on patients with poor ovarian response in vitro fertilization and embryo transfer (IVF-ET).Methods:206 clinical cases undergoing IVF-ET were analyzed retrospectively.According to the different administration,they were divided into two groups:109 cycles treated with letrozole plus HMG (mini-stimulation group)and 97 cycles treated with GnRH-a plus Gn (short-stimulation group).Compare the general condition,promoting ovulation rate and the pregnant outcome in each group.Results:There was significant differences between the short-stimulation group and the mini-stimulation group in the duration and the total dose of gonadotropin,Serum E2 levels on the day of HCG injection and the number of follicles which was ≥16 mm (P＜0.05).And there was no significant difference between the two groups in maturation rate,fertilization rate,cleavage rate,circle canceling rate and clinical pregnancy rate between the two groups (P ＞ 0.05),while the good-quality embry rate was significantly increased in the mini-stimulation group (P ＜ 0.01).Conclusions:Mini-stimulation protocol of letrozole is an preferable option for the poor ovarian response infertile patients.关键词
来曲唑微刺激/短方案/卵巢低反应Key words
Letrozole mini-stimulation protocol/ Short protocol/ Poor ovarian response分类
医药卫生引用本文复制引用
林敏,刘林丽,陈华,吕杰强..来曲唑微刺激方案和短方案对卵巢低反应助孕的临床研究[J].实用妇产科杂志,2013,29(7):536-538,3.
