生殖医学杂志2013，Vol.22Issue(7)：509-513,5.DOI:10.3969/j.issn.1004-3845.2013.07.009
体外受精-胚胎移植中三种不同的促排方法临床疗效和经济性的比较分析
Comparison of clinical efficacy and cost-effectiveness of IVF-ET cycles with three different protocols of controlled ovarian hyperstimulation
毕晓英 1王丹丹 1赵瑞钦1
作者信息
- 1. 河南中医学院第三附属医院,河南郑州450007
- 折叠
摘要
Abstract
Objective:To compare the clinical efficacy and the cost-effectiveniss of in vitro fertilization embryotransfer(IVF-ET)with three different protocols for controlled ovarian hyperstimulation.Methods:A total of 242 IVF/ICSI-ET cycles in infertility patients who received their treatment in our reproductive centre from January to November 2012 were analyzed retrospectively.They were divided into three groups according to ovarian stimulation protocol:rFSH group (gonal-F group,102 patients),uFSH group (urofollitropin group,82 patients) and uFSH+ HMG group(urofollitropin+ HMG group,58 patients).The clinical outcomes were compared among the three groups.Results:The duration of gonadotropin stimulation,estradiol levels on HCG day,numbers of retrieved oocytes,fertilization rate,the number of transferable embryos,clinical pregnancy rate,implantation rate,abortion rate and incidence of ovarian hyperstimulation syndrome were not significantly different among the three groups(P＞0.05).The total gonadotropin dose and the overall cost of gonadotropin in uFSH+HMG group were significantly less than those in the other two groups(P＜0.05).Conclusions:The u-FSH and r-FSH have the same effectiveness in ovarian stimulation in IVF-ET cycles.When u-FSH is used in combination with HMG,the clinical effectiveness is improved and the cost is reduced.关键词
重组卵泡刺激素/尿源性卵泡刺激素/人绝经期促性腺激素/控制性促排卵Key words
Recombinane follicle-stimulating hormone/ Urinary gonadotropin/ Controlled ovarian hyperstimulation引用本文复制引用
毕晓英,王丹丹,赵瑞钦..体外受精-胚胎移植中三种不同的促排方法临床疗效和经济性的比较分析[J].生殖医学杂志,2013,22(7):509-513,5.
