新医学2013，Vol.44Issue(6)：434-436,3.DOI:10.3969/g.issn.0253-9802.2013.06.019
蓝色橡皮大疱痣综合征一例报告
Blue rubber bleb nevus syndrome: a rare cause of gastroenterol bleeding
缪惠标 1陶力 1田虹1
作者信息
- 1. 510630广州,中山大学附属第三医院消化内科
- 折叠
摘要
Abstract
Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder characterized by multiple venous malformations,with unknowed etiology.Herein,we report a thirty-four years old woman with multiple blue cutaneous masses for over 20 years,who had suffered melena and bloody stool for two years.She had severe anemia and had to receive blood transfusion for a long term.CT scan of abdomen showed a large number of nodular lesions in liver,kidney,uterus,pelvic cavity and gluteus maximus.Angiography confirmed those lesion as venous malformations.Gastroscopy,colonoscopy,capsule endoscopy show nearly over 150 venous malformations throughout gastrointestinal tract and some of them were bleeding.Therapy included semi-flow and soft diet,iron supplement,and oral thalidomide.HGB of the patient increased from 56 g/L to 102 g/L.Dominant gastrointestinal bleeding disappeared and her condition remained well during two years of follow-up.Finally,she died of pyelonephritis and septicemia.It is extremely rare with so many lesions in gastrointestinal tract among the cases with BRBNS ever reported.Thalidomide is worthy to be used to control multiple centers bleeding.关键词
蓝色橡皮大疱痣综合征/静脉畸形/沙利度胺Key words
Blue rubber bleb nevus syndrome/ Venous malformation/ Thalidomide引用本文复制引用
缪惠标,陶力,田虹..蓝色橡皮大疱痣综合征一例报告[J].新医学,2013,44(6):434-436,3.
