新医学2013，Vol.44Issue(7)：495-498,4.DOI:10.3969/g.issn.0253-9802.2013.07.016
光动力疗法治疗黄斑区脉络膜新生血管临床观察
Clinical study of photodynamic therapy for macula choroidal neovascularization
吴斌斌 1高汝龙 1姚翠群 1汤云霞 1林晓梅 1李梦媛 1邓一鹏1
作者信息
摘要
Abstract
Objectives To observe the clinical efficacy of verteporfin photodynamic therapy (PDT)for in patients with macular choroidal neovascularization (CNV).Methods Forty five eyes of forty patients with CNV were analyzed retrospectively.All patients had been diagnosed with macular CNV by fundus fluorescein angiography (FFA),indole green choroid angiography(ICGA) and optical coherence tomography(OCT).Visiou,ocular fundus and OCT were observed at 12 weeks and 24 weeks after PDT.Results Twelve weeks after PDT,visual acuity improved in 10 eyes (22.2％),keep no change in 35 eyes (77.8％),no eye had vision loss.The result of FFA/ICGA showed:no leakage of CNV in 21 eyes (46.7％),less leakage of CNV in 15 eves (33.3％),CNV recurrence in 9 eyes (20.0％).At 24 weeks after treatment,visual acuity improved in 23 eyes (51.1％),remained unchange in 23 eyes (46.7％) and vision loss was found in 1 eye.Forty eyes (88.9％) had CNV closure,5 eyes (11.1％) had recurrent CNV.No adverse reactions were observed during follow-up.Conclusions PDT is a safe and effective treatment for macular CNV,which can reduce leakage of CNV.关键词
光动力疗法/黄斑/脉络膜新生血管Key words
Photodynamic therapy/ Macula/ Choroidal neovascularization引用本文复制引用
吴斌斌,高汝龙,姚翠群,汤云霞,林晓梅,李梦媛,邓一鹏..光动力疗法治疗黄斑区脉络膜新生血管临床观察[J].新医学,2013,44(7):495-498,4.
