中国临床心理学杂志2013，Vol.21Issue(3)：363-367,5.
癫痫患者默认网络的静息态功能磁共振成像研究
A Resting-state Functional Magnetic Resonance Imaging Analysis of Default Mode Network in Epileptics
摘要
Abstract
Objective:To analyze the default mode network (DMN) and its latent structure of epileptics in resting-state functional magnetic resonance imaging (fMRI).Methods:The resting-state fMRI data of 15 clinically primary epileptics and 20 normal volunteers were analyzed by independent component analysis.We selected independent component according to the best-sit criterion and analyzed the DMN network of grouping sufferers and normal samples.Finally,we constructed a functional connecting network from the chosen 11 encephalic regions in DMN with graph theory and clustering methods.Results:The encephalic region in DMN of sufferers dramatically fell and their functional connectivity network had obvious change along with the whole network presenting disordered hierarchical structure.Conclusion:The DMN and its latent hierarchical structure of epileptics in resting-state present disordered.关键词
癫痫/静息态/默认网络/功能连接/层次化结构Key words
Epilepsy/ Resting-state/ Default mode network/ Functional connectivity/ Hierarchical structure分类
医药卫生引用本文复制引用
张喆,柯铭,刘光耀,杨晓萍,陈旭辉..癫痫患者默认网络的静息态功能磁共振成像研究[J].中国临床心理学杂志,2013,21(3):363-367,5.基金项目
国家自然科学基金项目(61065007,61263047) （61065007,61263047）
甘肃省自然科学基金(0916RJZA020) （0916RJZA020）
兰州理工大学博士基金项目(BS14200901) （BS14200901）
