中国临床医学2013，Vol.20Issue(3)：283-286,4.
肺血管阻力对系统性红斑狼疮患者右心功能减退的预测效果
Novel Predictor for Evaluating Right Ventricular Dysfunction in Patients with Systemic Lupus Erythematosus:Pulmonary Vascular Resistance
赵航 1沈学东 1宋秀兰 1乔志卿 1徐婷嬿 1何奔 1程蕾蕾2
作者信息
- 1. 上海交通大学医学院附属仁济医院心内科,上海 200127
- 2. 复旦大学附属中山医院超声心动图室,上海市心血管病研究所,上海市影像医学研究所,上海200032
- 折叠
摘要
Abstract
Objective:To evaluate the value of ultrasonic cardiogram pulmonary vascular resistance (PVR) in the prediction of right ventricular dysfunction in patients with systemic lupus erythematosus (SLE).Methods:Forty-three SLE patients were divided into two groups according to the pulmonary artery systolic pressure (PASP) measured by echocardiography:group A (23patients with PASP ≤ 30 mmHg) and group B (20 patients with PASP＞ 30 mmHg).All patients underwent corresponding laboratory tests.PVR and fractional area change (FAC) were detected by ultrasonic cardiogram.Results:There were significant differences in 12 indexes between the two groups (P＜0.01).Taking FAC＜35％ as a dependent variable,after adjustment for age and gender,PVR was still related to right ventricular dysfunction(odds ratio =9.85,P =0.04)by multivariate logistic regression analysis.Receiver operator characteristic curve (ROC) analysis showed that the sensitivity and specificity for PVR＞1.45 wood in predicting FAC＜ 35％ were 92％ and 68％ (AUC:0.91,P＜0.001),respectively.Conclusions:PVR is a more accurate and sensitive predictor for right ventricular dysfunction compared with PASP.关键词
肺血管阻力/系统性红斑狼疮/右心功能Key words
Pulmonary vascular resistance/Systemic lupus erythematosus/Right ventricular function分类
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赵航,沈学东,宋秀兰,乔志卿,徐婷嬿,何奔,程蕾蕾..肺血管阻力对系统性红斑狼疮患者右心功能减退的预测效果[J].中国临床医学,2013,20(3):283-286,4.
