中国临床医学2013，Vol.20Issue(3)：343-345,3.
多囊卵巢综合征患者情绪障碍研究
Study of Polycystic Ovary Syndrome with Depression and Anxiety Symptoms
摘要
Abstract
Objective:To investigate the incidences of depression and anxiety in patients with polycystic ovary syndrome (PCOS) and their clinical characteristics.Methods:A total of 100 patients with PCOS aged 19～40 years were enrolled in this study.The anthropometric measurements,endocrinometabolic profiles,self-rating depression scale(SDS) and self-rating anxiety scale(SAS) were detected.Results:In 100 patients with PCOS,28(28％) patients had depression or anxiety symptoms (1 patient only had anxiety symptom,13 patients had depression symptom and 14 patients had both depression and anxiety symptoms).SDS and SAS scores in group with depression and/or anxiety symptoms were 58.70 ± 5.37 and 51.53 ± 8.07,respectively,which were significantly higher than those in group without depression and anxiety symptoms [41.10 ± 6.37 and 36.63 ± 5.64],respectively (all P＜0.01).Prolactin(PRL) and cortisol(F) in group with both depression and anxiety symptoms were (16.20 ± 10.77)ng/mL and (228.3 ± 36.3)μg/dL,respectively,which were higher than those in group without depression or anxiety symptoms[(13.49 ± 6.35)ng/mL and (133.0 ± 51.3) μg/dL] and group with depression or anxiety symptoms[(8.93± 3.80)ng/mL and (103.8± 19.6)μg/L](all P＜0.05).Conclusions:Although no clear association was found in depression and anxiety symptoms with endocrinometabolic profiles,mild to midrange depression symptoms distinguishes in patients with PCOS and also coexist with anxiety symptoms.关键词
多囊卵巢综合征/抑郁/焦虑Key words
Polycystic ovary syndrome/Depression/Anxiety分类
医药卫生引用本文复制引用
马瓈琼,虞一萍,张敏,徐鸣,李昕..多囊卵巢综合征患者情绪障碍研究[J].中国临床医学,2013,20(3):343-345,3.基金项目
上海市科委医学引导类科技项目(编号:124119a4002) （编号:124119a4002）
