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白癜风患者血清甲状腺自身抗体水平研究

贾名妍 苗青 于伟 张艺杰

中国美容医学2013,Vol.22Issue(14):1503-1506,4.
中国美容医学2013,Vol.22Issue(14):1503-1506,4.

白癜风患者血清甲状腺自身抗体水平研究

Research on serum thyroid autoantibodies levels in patients with vitiligo

贾名妍 1苗青 1于伟 1张艺杰1

作者信息

  • 1. 郑州大学第一附属医院皮肤科 河南 郑州 450052
  • 折叠

摘要

Abstract

Objective To measure the level of the serum thyroid autoantibodies in patients with vitiligo and investigate the relationship between vitiligo and autoimmune thyroid diseases.Methods 40 patients with vitiligo were enrolled and 38 age-and sex-matched healthy individuals served as controls.The levels of TPOAb and TGAb of patients with vitiligo and controls were measured by chemiluminescent immunoassay.Results The positivity of TPOAb and TGAb in the serum of patients with vitiligo was higher than that in controls significantly.The positivity of TPOAb in patients with vitiligo was 25.00%,higher than that in controls (2.63% for TPOAb,P<0.05).The positivity of TGAb in patients with vitiligo was 22.50%,higher than that in controls(5.26% for TGAb,P<0.05).The positivity of TPOAb and TGAb in female patients with vitiligo was higher than that in male patients (P<0.05).The positivity of TPOAb and TGAb in patients with vitiligo in 21~30 years old was higher than that in patients with vitiligo in the other age (P<0.05).In the different clinical classification and clinical stage,there were no statistical differences in the positivity of TPOAb and TGAb in patients with vitiligo (P>0.05).Conclusions The positivity of TPOAb and TGAb in young female patients with vitiligo was high,and there were correlation between vitiligo and autoimmune thyroid diseases.Clinicians should be aware of the risk of the concurrence of vitiligo and autoimmune thyroid disease,and ensure early screening,early detection and early treatment.

关键词

白癜风/甲状腺自身抗体/自身免疫性甲状腺疾病

Key words

vitiligo/ thyroid autoantibodies/ autoimmune thyroid disease

分类

医药卫生

引用本文复制引用

贾名妍,苗青,于伟,张艺杰..白癜风患者血清甲状腺自身抗体水平研究[J].中国美容医学,2013,22(14):1503-1506,4.

中国美容医学

1008-6455

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