中国体外循环杂志2013，Vol.11Issue(2)：71-74,4.
先天性心脏病手术后并发多脏器功能障碍综合征的临床分析
Clinical analysis of multiple organ dysfunction syndrome in children after cardiac surgery
周智恩 1孙小圣 2熊霞霞 1冯君 1陈红英 1何伦德 1王道庄 1邓硕曾1
作者信息
- 1. 610031成都,成都心血管病医院重症医学科
- 2. 610017成都,成都市中西医结合医院重症医学科
- 折叠
摘要
Abstract
Objective To invesrigate the high risk factors and methods for prevention and treatment of multiple organ dysfunction syndrome (MODS) in children after cardiopulmonary bypass (CPB).Methods From Jan.2001 to Dec.2010,there were total 35 children (21 males and 14 females) complicated with MODS after cardiac surgery in our department,and these cases were divided into two groups:death group and survival group.The high risk factors results in death,and the relationship between the MODS score and the fatality rate were compared and analyzed.Results The overall mortality rate was 51.4％ (18/35).(1) The incidence rate of cardiovascular,respiratory,renal,heparic,hematologic and neurologic dysfunction was 100.0％ (35/35),80.0％ (28/35),60.0％ (21/35),14.3％ (5/35),11.4％ (4/35) and 5.7％ (2/35) respectively.Cardiac and respiratory injury appeared much earlier than other organs.(2) The more dysfunction organ systems presented,the higher mortality rate of patients would be.Furthermore,there was a significant positive correlation between clinic score and mortality rate.(3) Compared with survivals group,the death group had longer CPB time,longer aortic clamping time and higher incidence of repeat CPB support during surgery and perioperative unexpected events (P ＜0.01).Conclusion Cardiac and respiratory dysfunction are the primary diseases in children with MODS after CPB.Mortality associated with MODS is highly correlated with the number of organ failing and clinical score.The high risk factors for the death of patients with MODS are the CPB rime,incidence of repeat CPB support during surgery and perioperative unexpected events.关键词
小儿/体外循环/多脏器功能障碍综合征/临床分析Key words
Children/ Cardiopulmonary bypass/ Multiple organ dysfunction syndrome/Clinical analysis分类
医药卫生引用本文复制引用
周智恩,孙小圣,熊霞霞,冯君,陈红英,何伦德,王道庄,邓硕曾..先天性心脏病手术后并发多脏器功能障碍综合征的临床分析[J].中国体外循环杂志,2013,11(2):71-74,4.
