中国体外循环杂志2013，Vol.11Issue(2)：75-78,4.
婴幼儿体外循环中人工胶体液代替血浆的综合评价
Replacement of plasma with artificial colloids in infants undergoing open heart surgery with cardiopulmonary bypass
赵明霞 1冯正义 1赵举 1胡金晓 1崔永丽 1龙村 1刘晋萍 1胡盛寿2
作者信息
- 1. 100037北京,中国医学科学院北京协和医学院国家心血管病中心阜外心血管病医院体外循环科
- 2. 100037北京,中国医学科学院北京协和医学院国家心血管病中心阜外心血管病医院心外科
- 折叠
摘要
Abstract
Objective To discuss the effect and safety of the replacement of plasma with artificial colloids in infants over 8 Kg undergoing heart surgery with cardiopulmonary bypass (CPB).Methods 90 infant patients undergoing heart surgery with CPB were divided into 3 groups randomly.4％ succinylated gelatin (Gelofusine),6％ hydroxyethyl starch 130/0.4 (Voluven) or plasma were primed for CPB respectively and the largest usage was 20 ml/kg.Colloid osmotic pressure,hemoglobin amount,platelet count,albumin amount,total protein amount,urea nitrogen level,creatinine level,ultrafiltration volume,urine volume and chest-tube drainage volume at several points,together with supportively ventilative time and ICU stay time were recorded and statistically analyzed.Results There was no difference in hemoglobin amount,platelet count,albumin amount,total protein amount,urea nitrogen level,creatinine level,ultrafiltration volume,urine volume and chest-tube drainage volume among 3 groups (P ＜0.05).Colloid osmotic pressure was higher in priming fluid containing Gelofusine or Voluven (P ＜ 0.05),while there was no difference in plasma colloid osmotic pressure among 3 groups (P ＞0.05).Both supportively ventilative time and ICU stay time were shorter in Gelofusine group and Voluyen group than in plasma group with no significant differences.Conclusion Replacement of plasma with Gelofusine or Voluven can be used for infant patients over 8 kg.The largest usage of 20 ml/kg is safe during CPB.We should make further study on coagulation function of infant patients using Gelofusine or Voluven for priming in future.关键词
体外循环/婴幼儿/人工胶体/预充液Key words
Cardiopulmonary bypass/ Infant/ Artificial colloid/ Priming solution分类
医药卫生引用本文复制引用
赵明霞,冯正义,赵举,胡金晓,崔永丽,龙村,刘晋萍,胡盛寿..婴幼儿体外循环中人工胶体液代替血浆的综合评价[J].中国体外循环杂志,2013,11(2):75-78,4.
