中国药业2013，Vol.22Issue(14)：77-78,2.
浊点萃取法提取青蒿中青蒿素的工艺研究
Technology Research on Artemisinin Extraction from Artemisia Annua L.by Cloud Point Extraction
况刚 1杨林 1郑小平 1何丹2
作者信息
- 1. 重庆市食品药品检验所,重庆 410021
- 2. 重庆医科大学药学院,重庆 400016
- 折叠
摘要
Abstract
Objective To establish the optimal extraction technology of artemisinin from Artemisia annua L.by the cloud point extraction(CPE) method.Methods The CPE method was adopted to extract artemisinin and the UV spectrophotometry was adopted to detect the content.The orthogonal experiment method was used to determine the effect of the surfactant concentration,solid-liquid ratio and balance time on the extraction efficiency for optimizing the optimal extractive technology.Results Adopting non-ion surfactant polyoxyethylene aliphatic alcohol ether(Genapol-X 80) with the concentration of 15.0％,the solid-liquid ratio of 100:1 and 2.0 mol/L NaCl,the extraction for 40 min under 60 ℃ could reach the highest extraction rate.Compared with the traditional technology,the CPE method greatly increased the extraction rate.Conclusion The CPE method is stable,feasible and simple to operate,and avoids the high temperature destroy with green,environment protection and high extraction rate.关键词
青蒿/青蒿素/浊点萃取Key words
Artemisia annua L./artemisinin/cloud point extraction分类
化学化工引用本文复制引用
况刚,杨林,郑小平,何丹..浊点萃取法提取青蒿中青蒿素的工艺研究[J].中国药业,2013,22(14):77-78,2.
